Form 8-K

UNITED STATES

SECURITIES AND EXCHANGE COMMISSION

WASHINGTON, D.C. 20549

 


FORM 8-K

 


CURRENT REPORT

PURSUANT TO SECTION 13 OR 15(D) OF THE SECURITIES EXCHANGE ACT OF 1934

Date of Report (Date of earliest event reported): January 12, 2007

 


Arrowhead Research Corporation

(Exact name of registrant as specified in its charter)

 


0-21898

(Commission File Number)

 

Delaware   46-0408024

(State or other jurisdiction

of incorporation)

 

(IRS Employer

Identification No.)

201 South Lake Avenue, Suite 703, Pasadena, CA 91101

(Address of principal executive offices) (Zip Code)

Registrant’s telephone number, including area code (626) 304-3400

 


Check the appropriate box below if the Form 8-K filing is intended to simultaneously satisfy the filing obligation of the registrant under any of the following provisions:

 

¨ Written communications pursuant to Rule 425 under the Securities Act (17 CFR 230.425)

 

¨ Soliciting material pursuant to Rule 14a-12 under the Exchange Act (17 CFR 240.14a-12)

 

¨ Pre-commencement communications pursuant to Rule 14d-2(b) under the Exchange Act (17 CFR 240.14d-2(b)

 

¨ Pre-commencement communications pursuant to Rule 13e-4 (c) under the Exchange Act (17 CFR 240.13e-4(c)

 



Item 8.01. Other Events.

On January 12, 2007 the Company distributed its 2007 Annual Report with a Letter to Shareholders from the Chairman of the Board (the “Letter to Shareholders”).

The Letter to Shareholders is attached as Exhibit 20.1 hereto.

Item 9.01. Financial Statements and Exhibits.

(c) Exhibits.

 

Exhibit No.   

Description

20.1    Letter to Shareholders dated January 12, 2007


SIGNATURES

Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned thereunto duly authorized.

 

Date: January 19, 2007    
  ARROWHEAD RESEARCH CORPORATION
  By:  

/s/ Joseph T. Kingsley

    Joseph T. Kingsley, Interim President and Chief Financial Officer
Letter to Shareholders

Exhibit 20.1

To Our Shareholders,

I am pleased to report another successful year on the path to building a major enterprise in the burgeoning field of nanotechnology. We began the year by securing an additional $20 million in financing from institutional investors. The purpose of the capital infusion was to facilitate commercialization of products by our majority-owned subsidiaries and expand our portfolio of subsidiaries and university research collaborations.

We employed some of this capital to expand our activities in the nanomedical arena, where nanotechnology is enabling revolutionary approaches to treating disease. At the end of February 2006, our majority-owned subsidiary Insert Therapeutics received approval from the FDA to begin trials at the City of Hope with its first cancer product, IT-101. Phase I clinical trials commenced in the summer and are expected to be completed by mid 2007. In late FY 2006, Arrowhead was the lead investor in a $10 million financing for Insert Therapeutics which closed in October 2007.

RNAi enjoyed a heightened profile this year with the award of the Nobel Prize to its discoverers. We increased our ownership position in majority-owned subsidiary Calando Pharmaceuticals and committed an additional $10 million to further the development of its anti-cancer RNAi therapeutic. Calando is now performing preclinical studies and preparing to file an investigational new drug application with the FDA. The capital was provided to both Insert and Calando because they met their milestones in seeking to bring nanoparticle-based therapeutics to market.

We made a strategic decision to expand our presence in the new market opportunities being created by carbon nanotubes. NanoPolaris, our wholly owned subsidiary that consolidated exclusive rights to intellectual property covering carbon nanotubes, acquired the assets of Unidym, a company developing electronic products based on carbon nanotubes. NanoPolaris changed its name to Unidym and Arrowhead committed $7 million to scale the manufacturing process for Unidym’s first product.

In FY 2006, we continued to work with researchers at Caltech, Duke, and Stanford to further develop nanotechnologies to address different markets. We also expanded our research program by initiating a development agreement with the University of Florida for carbon-based printable electronics.

We believe Arrowhead is on course to generate significant value for our shareholders. In addition to our business and technical progress, we ended the year with a strong cash position to enable us to continue to implement our current and future objectives. In FY 2007, we expect to add to our portfolio of subsidiary companies, to announce the filing of a new IND application with the FDA to begin clinical trials of another drug candidate, to expand our university research program and to engage in several collaborative development deals with major corporations.

 

Sincerely,

/s/ R. Bruce Stewart

R. Bruce Stewart

Chairman & Chief Executive Officer